Summary information
Study title
Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015
Creator
Kvale, Dag (Oslo universitetssykehus)
Study number / PID
https://doi.org/10.18712/NSD-NSD2268-V2 (DOI)
Data access
Information not available
Series
Not available
Abstract
The study is a prospective controlled study of HIV seropositive patients investigating whether an anti-inflammatory COX-2 inhibitor (etoricoxib) given respectively 2 and 24 weeks improves the ability of the immune response against T cell-dependent vaccines in in proportion to a control group. The project will also examine (i) effects on HIV-associated chronic immune activation, one pathogenetic unfortunate "driver" of HIV infection associated with rapid progression of HIV and cardiovascular risk; (ii) effect on HIV-specific immunity.
Topics
Keywords
Methodology
Data collection period
12/01/2011 - 07/01/2015
Country
Time dimension
Not availableAnalysis unit
Individual
Universe
Voluntary HIV-seropositive individuals who fill inclusion criteria and no exclusion criteria according to protocol.
Sampling procedure
Not availableKind of data
Other
Data collection mode
Not availableFunding information
Funder
The Research Council of Norway
Grant number
192514
Funder
Oslo University Hospital
Access
Publisher
Sikt - Norwegian Agency for Shared Services in Education and Research
Publication year
2024
Terms of data access
Not availableRelated publications
Not available