2026-06-02T07:20:15Z https://datacatalogue.cessda.eu/oai-pmh/v0/oai

e9bbb41eb903f5003121ef574db00e40c04647309bf7473473584b656f9c6b10 2026-03-30T02:24:59Z language:enopenaire_data

MRS psychotherapy study MRS psychotherapy study af7c9cd6-8fd6-46db-af93-7181955cde3c10.48573/kfpv-pt95 Böker, Heinz Kleim, Birgit FORSFORSFORS 2023 PSYCHOLOGIEPSYCHOLOGYPSYCHOLOGIE Depression is the leading cause of disability worldwide. Psychotherapy is an integral part of depression treatment, however rates of response and remission remain limited. Research on the neurobiological mechanisms involved in depression may contribute to a better understanding of recovery processes and inform a more targeted use of treatments. To date, critical gaps in the knowledge of the neurobiology of depression remain and the neurobiological mechanisms involved in its psychotherapeutic treatment are poorly understood. The aim of this study is to identify specific neurofunctional and neurochemical brain alterations in depression and the effects of psychotherapy on these alterations. We employed functional magnetic resonance imaging and magnetic resonance spectroscopy in two samples: A) 56 depressed participants compared to 52 healthy controls were assessed once; and B) 32 depressed patients were assessed before and after six months of once a week psychotherapy and compared to 30 healthy controls. SchweizSwitzerlandSuisseWesteuropaWestern EuropeEurope occidentaleEuropaEuropeEurope Additional data use purposes: Research purposesZusätzliche Datennutzungszwecke: ForschungszweckeFinalités supplémentaires d’utilisation des données: Fins de rechercheSondergenehmigung: Nach vorheriger Zustimmung des AutorsSpecial permission: With prior agreement of authorPermission spéciale: Accord préalable de l'auteur·trice swissubase_2266_1_0 MRS psychotherapy study: Data MRS psychotherapy study: Information on data http://www.swissubase.ch/oai-pmh/v1/oai oai:swissubase.ch:af7c9cd6-8fd6-46db-af93-7181955cde3c 2026-03-24T12:04:32Z ddi:codebook:2_5