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          <titl xml:lang="sv">Betula - åldrande, minne och demens: 2013-2014 (testvåg 6)</titl>
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        <titl xml:lang="sv">Betula - åldrande, minne och demens: 2013-2014 (testvåg 6)</titl>
        <parTitl xml:lang="en">The Betula Project - Aging, memory and dementia - Betula - aging, memory and dementia: 2013-2014 (test wave 6)</parTitl>
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        <AuthEnty affiliation="Integrative Medical Biology, Umeå University" xml:lang="en">Nyberg, Lars
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        </AuthEnty><AuthEnty affiliation="Department of Psychology , Stockholm University" xml:lang="en">Nilsson, Lars-Göran
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        </AuthEnty><AuthEnty affiliation="Psyciatry, Umeå university" xml:lang="en">Adolfsson, Rolf
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xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D017530">Health Care Quality, Access, and Evaluation</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D017530">Vårdkvalitet, tillgång och utvärdering</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D040342">Genetic Structures</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D040342">Genetiska strukturer</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D052180">Publication Formats</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D052180">Publikationsformer</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055641">Mathematical Concepts</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055641">Matematiska begrepp</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D004191">Behavioral Disciplines and Activities</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D004191">Beteendevetenskapliga discipliner och aktiviteter</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005159">Health Care Facilities, Manpower, and Services</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005159">Hälso- och sjukvårdsinrättningar, arbetskraft och tjänster</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008433">Mathematics</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008433">Matematik</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D009934">Organization and Administration</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D009934">Organisation och administration</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D011320">Primary Health Care</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D011320">Primärvård</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D003191">Comprehensive Health Care</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D003191">Heltäckande vård</keyword><keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D010346">Patient Care Management</keyword><keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D010346">Patientadministration</keyword>
        <topcClas xml:lang="en" vocab="Standard för svensk indelning av forskningsämnen 2011">Medical and Health Sciences</topcClas><topcClas xml:lang="sv" vocab="Standard för svensk indelning av forskningsämnen 2011">Medicin och hälsovetenskap</topcClas><topcClas xml:lang="en" vocab="Standard för svensk indelning av forskningsämnen 2011">Geriatrics</topcClas><topcClas xml:lang="sv" vocab="Standard för svensk indelning av forskningsämnen 2011">Geriatrik</topcClas><topcClas xml:lang="en" vocab="CESSDA Topic Classification" vocabURI="https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=Health.GeneralHealthAndWellbeing">General health and well-being</topcClas><topcClas xml:lang="sv" vocab="CESSDA Topic Classification" vocabURI="https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=Health.GeneralHealthAndWellbeing">Allmän hälsa och välbefinnande</topcClas><topcClas xml:lang="en" vocab="Standard för svensk indelning av forskningsämnen 2011">Clinical Medicine</topcClas><topcClas xml:lang="sv" vocab="Standard för svensk indelning av forskningsämnen 2011">Klinisk medicin</topcClas><topcClas xml:lang="en" vocab="CESSDA Topic Classification" vocabURI="https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=Health">HEALTH</topcClas><topcClas xml:lang="sv" vocab="CESSDA Topic Classification" vocabURI="https://vocabularies.cessda.eu/vocabulary/TopicClassification?code=Health">HÄLSA</topcClas>
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      <abstract xml:lang="en">The Betula Project is a longitudinal study of aging, memory and dementia. Data was collected between 1988 - 2014. For each test wave participants completed a thorough physical examination with blood tests of a nurse and a careful examination of a memory tester. There are data collected from approximately 4,700 participants. On each occasion, data for about 2000 variables were collected for each participant, which includes data on demographics, health, illness, medication, social and cognitive factors. The Betula project has received funding for research infrastructures (large databases) from the Swedish Research Council. This means a major effort to make the Betula database available to researchers outside the project through collaborations with researchers within the Betula project. To the Betulas database, genetic data and biological samples are also connected.  Purpose:  Study how memory functions change during adult life, to identify risk factors for dementia and to identify early preclinical signs of dementia and determine the critical factors of successful aging.  Besides tests and forms that was colledcted at Health- and Memory session, MRI-data (structural and functional) was also collected from 231 participants (out of the 376 that was collected at test wave 5).</abstract><abstract xml:lang="sv">Betulaprojektet är en longitudinell studie av åldrande, minne och demens. Insamlingen till projektet pågick mellan 1988 -2014.  Vid varje testtillfälle har varje deltagare genomgått en noggrann hälsoundersökning med blodprovstagning hos en sjuksköterska och en noggrann undersökning hos en minnestestare. Det finns data insamlat från ca 4700 deltagare. Vid varje tillfälle insamlas data för ungefär 2000 variabler för varje deltagare som inkluderar data om demografi, hälsa, sjukdom, medicinering, sociala faktorer och kognitiva faktorer. Betulaprojektet har fått bidrag för forskningsinfrastruktur (stora databaser) från Vetenskapsrådet. Det innebär en kraftig satsning på att bygga upp databasen för Betula och göra databasen tillgänglig även för forskare utanför projektet i form av samarbeten med forskare direkt kopplade till Betulaprojektet. Till Betulas databas är även kopplad gendata och biologiska prov.  Syfte: Studera hur minnesfunktioner förändras under vuxenlivet, att bestämma riskfaktorer för demens och tidigare prekliniska tecken på demens och att bestämma vilka de kritiska faktorerna av det goda åldrandet är.  Utöver tester och formulär som samlats in vid Hälso- och Minnestest samlades även MRI-data (strukturellt och funktionellt) in från 231 individer (av de 376 som samlades in vid testtillfälle 5).</abstract>
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        <sampProc xml:lang="en">1000 individuals in age groups 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 were randomly selected (sample 1, S1). There were 100 individuals i each age cohort, the gender distribution reflected the gender distribution in the population ie about as many men as women in the younger age groups and about twice as many women as men from age group 70 and above (test occasion 1, T1) In T2, five years later, two new samples were added to the group, S2  (ca 1000, age 35-80) and S3 (ca 960, age 40-85). At T3 sample 4 was added (ca 500, age 35-90). At T4, sample 5 was added (ca 500, age 35-95) and at T5 sample 6 was added (ca 350, age 25-80).<concept/></sampProc><sampProc xml:lang="sv">1000 personer i åldersgrupperna 35, 40, 45, 50, 55, 60, 65, 70, 75 och 80 blev slumpmässigt utvalda (sample 1, S1). Det ingick 100 personer i varje ålderskohort, könsfördelningen avspeglade könsfördelningen i populationen d.v.s ungefär lika många män som kvinnor i de yngre åldrarna, ungefär dubbelt så många kvinnor som män från åldersgruppen 70 och uppåt (testtillfälle 1, T1). Vid T2, fem år senare, inkallades ytterligare två sample, S2 (ca 1000 st, 35-80 år) och S3 (ca 960 st, 40-85 år). Vid T3 kallades sample 4 in (ca 500st, 35-90 år). Vid T4, kallades sampel 5 in (ca 500 st, 35-95 år) och vid T5 kallades sample 6 (ca 350st, 25-80 år).<concept/></sampProc><sampProc xml:lang="en">Probability: Stratified<concept/></sampProc><sampProc xml:lang="sv">Sannolikhetsurval: stratifierat urval<concept/></sampProc><sampProc xml:lang="en">Probability<concept/></sampProc><sampProc xml:lang="sv">Sannolikhetsurval<concept/></sampProc>
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