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DDI2.5 XML CODEBOOK RECORD FOR STUDY NUMBER 8131 International Study of Asthma and Allergies in Childhood, 1992-2005 813110.5255/UKDA-SN-8131-1 Strachan, D., University of London Pearce, N., London School of Hygiene and Tropical Medicine, Department of Medical Statistics Garcia-Marcos, L., University of Murcia (Spain), Department of Paediatrics Asher, I., University of Auckland, Department of Paediatrics, Child and Youth Health Copyright D. Strachan, I. Asher, N. Pearce and L. Garcia-Marcos UK Data Service 22 February 2017 ASTHMAALLERGIESCHILDRENDERMATITISRESPIRATORY TRACT DISEASESCOUGHINGCLINICAL TESTS AND MEASUREMENTSENVIRONMENTAL RISKHOUSEHOLD PETSLIVESTOCKCLEANINGHOUSING CONDITIONSMEDICAL CARESYMPTOMS YouthHealth care services and policiesSpecific diseases, disorders and medical conditions Abstract copyright UK Data Service and data collection copyright owner.The International Study of Asthma and Allergies in Childhood (ISAAC) was a worldwide epidemiological research programme established in 1991 to investigate asthma, rhinoconjunctivitis and eczema in children, due to considerable concern that these conditions were increasing in many countries, and that the causes of this increase were unknown. ISAAC Phase One was an international multi-centre cross-sectional study involving two age groups of school children, 13-14 year olds (adolescents) and 6-7 year olds (children). Schools were randomly selected from a defined geographical area. Written questionnaires on asthma, rhinitis and eczema symptoms (translated from English) were completed by the adolescents at school, and at home by the parents of the children. An asthma symptoms video questionnaire for the adolescents was optional. ISAAC Phase Two involved more intensive studies in a smaller number of selected centres. Children aged 8-12 years were examined for flexural dermatitis, underwent skin prick tests for atopy, bronchial responsiveness to hypertonic saline, blood sampling and storage for serum IgE and genetic analyses, and additional questionnaires were completed by their parents. ISAAC Phase Three, a repeat of Phase One after at least five years, examined variations in time trends of childhood asthma, rhinoconjunctivitis and eczema around the world, and expanded the world maps of these conditions. Additional questions on risk factors were included in Phase Three. The ISAAC programme grew to involve nearly 2 million children from 306 study centres in 105 countries, before it formally closed in December 2012. Further information about the study can be found on the <a href="http://isaac.auckland.ac.nz/story/index.html" title="ISAAC study">ISAAC</a> study website. Main Topics: Prevalence and severity of symptoms of asthma, rhinoconjunctivitis and eczema in schoolchildren. Individual risk factors for these conditions. Trends over time in prevalence of these conditions. June 1992 - March 200501 June 199201 March 2005 Multi-nation IndividualsCross-nationalNational Almost 2 million children aged 6-7 or 13-14 years from about 300 study centres in over 100 countries took part in either ISAAC Phase One or ISAAC Phase Three (questionnaire surveys). Over 50,000 children aged 8-12 years from 30 study centres in 23 countries took part in ISAAC Phase Two, which involved clinical tests for asthma and allergy as well as data collection by questionnaire. Numeric Repeated cross-sectional studyNot all centres took part in both Phase One and Phase Three, so information is available on a one-time basis from some centres and a repeated cross-sectional basis from others. Some centres undertook Phase Two in the same study area as Phase One (but in a different age group). Other centres in Phase Two are not represented in either Phase One or Phase Three. One-stage stratified or systematic random sampleIn Phase Two, some measurements in some centres were performed only on a stratified sample, with two strata: wheezy children and non-wheezy children. Postal surveySelf-completionClinical measurementsSelf-completion (at school) used for 13-14-year-olds. Postal questionnaire (distributed to parents via schools) used for younger age-groups. Clinical measurements restricted to Phase Two only. <img alt="Creative Commons License" style="border-width:0" src="https://beta.ukdataservice.ac.uk/assets/img/logo-cc.png" /></a>  The Data Collection is to be made available to any user without the requirement for registration for download/access under a <a href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International</a> Licence. See <restrctn> https://oai.ukdataservice.ac.uk:8443/oai/provider 8131 2024-11-28T07:31:20Z ddi:codebook:2_5