2026-10-15T09:04:34Z https://datacatalogue.cessda.eu/oai-pmh/v0/oai

8f429113ee176c3549c1e5ba54a1836a61d148a2d54cb9c467ca5d9c35e8dfaf 2026-06-02T15:22:44Z language:enopenaire_data

813110.5255/UKDA-SN-8131-1 http://doi.org/10.5255/UKDA-SN-8131-1 International Study of Asthma and Allergies in Childhood, 1992-2005 Strachan, D., University of LondonPearce, N., London School of Hygiene and Tropical Medicine, Department of Medical StatisticsGarcia-Marcos, L., University of Murcia (Spain), Department of PaediatricsAsher, I., University of Auckland, Department of Paediatrics, Child and Youth Health Abstract copyright UK Data Service and data collection copyright owner.The International Study of Asthma and Allergies in Childhood (ISAAC) was a worldwide epidemiological research programme established in 1991 to investigate asthma, rhinoconjunctivitis and eczema in children, due to considerable concern that these conditions were increasing in many countries, and that the causes of this increase were unknown. ISAAC Phase One was an international multi-centre cross-sectional study involving two age groups of school children, 13-14 year olds (adolescents) and 6-7 year olds (children). Schools were randomly selected from a defined geographical area. Written questionnaires on asthma, rhinitis and eczema symptoms (translated from English) were completed by the adolescents at school, and at home by the parents of the children. An asthma symptoms video questionnaire for the adolescents was optional. ISAAC Phase Two involved more intensive studies in a smaller number of selected centres. Children aged 8-12 years were examined for flexural dermatitis, underwent skin prick tests for atopy, bronchial responsiveness to hypertonic saline, blood sampling and storage for serum IgE and genetic analyses, and additional questionnaires were completed by their parents. ISAAC Phase Three, a repeat of Phase One after at least five years, examined variations in time trends of childhood asthma, rhinoconjunctivitis and eczema around the world, and expanded the world maps of these conditions. Additional questions on risk factors were included in Phase Three. The ISAAC programme grew to involve nearly 2 million children from 306 study centres in 105 countries, before it formally closed in December 2012. Further information about the study can be found on the <a href="http://isaac.auckland.ac.nz/story/index.html" title="ISAAC study">ISAAC</a> study website. Main Topics: Prevalence and severity of symptoms of asthma, rhinoconjunctivitis and eczema in schoolchildren. Individual risk factors for these conditions. Trends over time in prevalence of these conditions. ASTHMAALLERGIESCHILDRENDERMATITISRESPIRATORY TRACT DISEASESCOUGHINGCLINICAL TESTS AND MEASUREMENTSENVIRONMENTAL RISKHOUSEHOLD PETSLIVESTOCKCLEANINGHOUSING CONDITIONSMEDICAL CARESYMPTOMS en 2017-02-22T08:43:39Z Dataset Copyright D. Strachan, I. Asher, N. Pearce and L. Garcia-Marcos Multi-nation https://oai.ukdataservice.ac.uk:8443/oai/provider 8131 2024-11-28T07:31:20Z ddi:codebook:2_5