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          <titl xml:lang="sv">MISS-kohorten, Melanom i Södra Sverige - DNA</titl>
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        <titl xml:lang="sv">MISS-kohorten, Melanom i Södra Sverige - DNA</titl>
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        <AuthEnty affiliation="Faculty of Medicine, The Division of Oncology and Pathology, Lund University" xml:lang="en">Olsson, Håkan
        </AuthEnty><AuthEnty affiliation="Medicinska fakulteten, Avdelningen för onkologi och patologi, Lunds universitet" xml:lang="sv">Olsson, Håkan
        </AuthEnty><AuthEnty affiliation="Faculty of Medicine, Surgery, Lund University" xml:lang="en">Ingvar, Christian
        </AuthEnty><AuthEnty affiliation="Medicinska fakulteten, Avdelningen för kirurgi, Lunds universitet" xml:lang="sv">Ingvar, Christian
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      <abstract xml:lang="en">The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. The interviews were conducted between 1990 and 1992 and the questions concerned, among other things, the time for the woman's first menstruation, number of pregnancies, age at entry into menopause, contraception, alcohol, smoking, sun exposure and constitutional factors. The cohort was interviewed one more time in year 2000 and again 2011. Re-interviews are scheduled for every ten years. During 2011 to 2013 DNA was collected from the cohort through saliva. Follow-up of morbidity and mortality are made annually through the national registry.  Purpose:  The aim of this study was to create a prospective population-based cohort of women from Southern Sweden with information regarding environmental and genetic factors.</abstract><abstract xml:lang="sv">MISS-kohorten startades 1990 då 40 000 kvinnor mellan 26 och 65 år i Skåne slumpvis blev utvalda att delta i en intervju angående riskfaktorer för malignt melanom och bröstcancer. 29 508 (ca 74%) av de tillfrågade kvinnorna valde att delta. Ingen av kvinnorna hade tidigare drabbats av cancer. Intervjuerna utfördes mellan år 1990 och 1992 och frågorna berörde bl. a. tidpunkten för kvinnans första menstruation, antal graviditeter, ålder vid ingång i klimakteriet, preventivmedel, alkohol, rökning, solexponering samt kroppkonstitution. Kohorten intervjuades en ytterligare gång år 2000 och även år 2011. Återintervjuer är planerade till var tionde år. Under åren 2011 till 2013 samlades även DNA in från kohorten genom saliv. Uppföljning av morbiditet och mortalitet görs årligen via nationella register.  Syfte:  Syftet med studien var att skapa en prospektiv populationsbaserad kohort med kvinnor från Södra Sverige med information rörande miljöfaktorer och genetiska faktorer.  DNA från saliv har samlats in från &gt;50% av kohorten.</abstract>
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