2026-05-24T23:22:39Z https://datacatalogue.cessda.eu/oai-pmh/v0/oai

138ae3348a32a5f3a2387d8e51ef56fb37aefefb7b5067d625612649f585c872 2025-12-08T01:09:55Z language:enopenaire_data

Roux-en-Y gastric bypass in rat reduces mu-opioid receptor availability in brain regions associated with stress and energy regulation Roux-en-Y gastric bypass in rat reduces mu-opioid receptor availability in brain regions associated with stress and energy regulation doi:10.17026/DANS-22T-3TKDeasy-dataset:127153 P.K. Thanos 2018-11-01 DANS Data Station Social Sciences and Humanities 2019-05-16 Social Sciences <p>In this study, we sought to examine the mu opioid receptor levels throughout the brain following RYGB surgery, and whether these changes are the result of caloric restriction or an effect of the surgery itself. Following the experiment, mu-opioid receptor autoradiography was performed on the rat brain using the [3H] [D-Ala2,N-Me-Phe4-Gly5-ol]- enkephalin (DAMGO) ligand. Two CSV files are uploaded giving the individual measurements of binding (uCi/g) for each region analyzed with ImageJ software. A third file gives the compiled averages used to perform statistical analysis and create binding figures. A sample film with regions drawn in ImageJ is provided. Body weight data recorded throughout the experiment is given in a CSV file as well.</p> https://ssh.datastations.nl/oai doi:10.17026/DANS-22T-3TKD 2025-12-03T01:00:28Z ddi:codebook:2_5